Amy Sedaris (born March 29, 1961 in Endicott, New York) is an American actress and comedian. A former member of Chicago-based Second City and Annoyance Theatre comedy troupes, she is best known for her role as "Jerri Blank" in the television series Strangers with Candy, which she co-wrote with Paul Dinello and Stephen Colbert. The show was written around Sedaris' impression of 1970s motivational speaker Florrie Fisher, an impression which Sedaris has since developed into a stock character.

Sedaris has appeared in the movies Elf, School of Rock, and Maid in Manhattan and the film version of Bewitched and is featured in David Munro's upcoming Full Grown Men. She recently starred in the film adaptation of Strangers with Candy as Jerri Blank. In addition to acting, she runs a cupcake and cheese ball business ("Dusty Food Cupcakes") out of her kitchen.

Sedaris also hosted the series Film Fanatic on Trio. She coauthored the text-and-picture novel Wigfield with Paul Dinello and Stephen Colbert, published in 2003. As of 2005, Sedaris writes a monthly advice column in The Believer. She also is currently writing a guide to entertaining entitled I Like You: Hospitality Under the Influence, to be published in October 2006 by Warner Books.

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