"Mystery Train" was a 1955 single recorded at Sun Studios in Memphis, Tennessee by Elvis Presley, his first #1 single in any of the Billboard charts, reaching #1 in the Country music chart.
Mystery Train was originally recorded for Sun Records by Little Junior's Blue Flames in 1953.
The song has lent its name to several other works:

Apollo Movie Guide - Review, links, and cast information.
TV Guide Online: Mystery Train - Includes review, plot, and cast.
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